Can a researcher use de-identified biospecimens for a different study without re-consent from original subjects?

The rationale for choosing that response lies in the definition and treatment of de-identified biospecimens in research. When biospecimens are de-identified, personal identification information has been removed or altered so that the samples cannot be traced back to the individual from whom they were obtained. This process effectively excludes these samples from the definition of human subjects research, as they no longer involve identifiable private information about living individuals.

According to regulations, once biospecimens are de-identified, researchers do not need to obtain new consent from the original subjects for subsequent studies. This is rooted in the understanding that ethical obligations related to consent primarily apply when an individual's identifiable information is involved. Thus, utilizing de-identified biospecimens for different research purposes is permissible.

The other options highlight important ethical components regarding consent and human subjects research, but they do not accurately address the implications of de-identification in this context, which is critical to understanding the correct answer.